Summary of use during lactation
Xanomeline is a cholinergic antipsychotic agent that is available in combination with trospium, which is a peripheral anticholinergic agent. No information is available on the clinical use of xanomeline or trospium during breastfeeding. Because trospium is a charged molecule, it is unlikely to pass well into milk. If the mother requires xanomeline, it is not a reason to discontinue breastfeeding. Until more data are available, the xanomeline-trospium combination should only be used with careful infant monitoring, particularly for gastrointestinal side effects such as nausea, vomiting diarrhea, and reflux.
Drug levels in milk and infant serum
Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.
Effects in breastfed infants
Relevant published information was not found as of the revision date.
Effects on lactation and breastmilk
Relevant published information was not found as of the revision date.
Source: Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, NCBI Bookshelf. Check LactMed for the most recent revision.
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