Summary of use during lactation
No information is available on the clinical use of vutrisiran during breastfeeding. Because vutrisiran is a large oligonucleotide, the amount in milk is likely to be very low and absorption by the infant is probably minimal. If vutrisiran is required by the mother, it is not a reason to discontinue breastfeeding. Until more data become available, use vutrisiran with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Drug levels in milk and infant serum
Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.
Effects in breastfed infants
Relevant published information was not found as of the revision date.
Effects on lactation and breastmilk
Relevant published information was not found as of the revision date.
Source: Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, NCBI Bookshelf. Check LactMed for the most recent revision.
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