Vilanterol and Breastfeeding

Summary of use during lactation

Although no published data exist on the use of vilanterol during lactation, data from the related drug, terbutaline, indicate that very little is expected to be excreted into breastmilk.[1] Vilanterol is available only in combination products such as Breo Ellipta and Anoro Ellipta. The authors of several reviews agree that use of inhaled bronchodilators is acceptable during breastfeeding because of the low bioavailability and maternal serum levels after use.[2-4] Combination products such as Breo Ellipta and Anoro Ellipta are likely to be acceptable for similar reasons.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

Alternative drugs to consider

Formoterol, Salmeterol

References

1. Lindberg C, Boréus L, de Château P, et al. Transfer of terbutaline into breast milk. Eur J Respir Dis Suppl 1984;134:87-91.6586490 PubMed
2. McDonald C, Burdon J. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust 1996;165:485-8.8937369 PubMed
3. Nelson-Piercy C. Asthma in pregnancy. Thorax 2001;56:325-8.11254828 PubMed
4. Taddio A, Ito S. Drugs and breast-feeding. In, Koren G, ed. Maternal-fetal toxicology. A clinician's guide. 3rd ed. New York. Marcel Dekker. 2001:177-32.