Urea C 14 and Breastfeeding

Summary of use during lactation

Information in this record refers to the use of urea C 14 as a diagnostic agent. No information is available on the use of urea C 14 during breastfeeding. However, administration of urea C 14 directly to pediatric patients is considered to be safe.[1] International guidelines state that breastfeeding need not be interrupted after administration of urea C 14.[2]

Drug levels in milk and infant serum

Carbon 14 is a low-energy beta emitter with a physical half-life of about 5730 years.[3]

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

Alternative drugs to consider

Urea C 13

References

1. PathakCM KaurB KhandujaKL 14C-urea breath test is safe for pediatric patients. Nucl Med Commun 2010 31 830 5 20864821 PubMed
2. MattssonS JohanssonL Leide SvegbornS Radiation dose to patients from radiopharmaceuticals: A compendium of current information related to frequently used substances. ICRP Publication 128. Annex D. Recommendations on breast-feeding interruptions. Ann ICRP 2015 44 2 Suppl 319 21 26069086 PubMed
3. Leide-SvegbornS AhlgrenL JohanssonL Excretion of radionuclides in human breast milk after nuclear medicine examinations. Biokinetic and dosimetric data and recommendations on breastfeeding interruption. Eur J Nucl Med Mol Imaging 2016 43 808 21 26732471 PubMed