Sugammadex and Breastfeeding

Summary of use during lactation

No information is available on the clinical use of sugammadex during breastfeeding. Because sugammadex is a large, highly polar molecule with a molecular weight of 2002 Da., the amount in milk is likely to be very low and oral absorption by the infant is unlikely. Sugammadex is acceptable to use during breastfeeding.[1-3]

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

Alternative drugs to consider

Neostigmine

References

1. Reece-StremtanS CamposM KokajkoL ABM Clinical Protocol #15: Analgesia and anesthesia for the breastfeeding mother, revised 2017. Breastfeed Med 2017 12 500 6 29624435 PubMed
2. RichardsonMG RaymondBL Sugammadex administration in pregnant women and in women of reproductive potential: A narrative review. Anesth Analg 2020 130 1628 37 31283616 PubMed
3. HirschJG ChiaPA JahrJS Sugammadex: A review of the considerations for women of childbearing age. Am J Ther 2023 30 e146 e150 36892560 PubMed