Phenelzine and Breastfeeding

Summary of use during lactation

Because of the lack of data on use during breastfeeding, other antidepressants are preferred during breastfeeding.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Phenelzine can elevate serum prolactin in some patients and has caused galactorrhea in nonpregnant, nonnursing patients.[1,2] The clinical relevance of these findings in nursing mothers is not known. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternative drugs to consider

Nortriptyline, Paroxetine, Sertraline

References

1. CokerF TaylorD. Antidepressant-induced hyperprolactinaemia: Incidence, mechanisms and management. CNS Drugs 2010 24 563 74 20527996 PubMed
2. SegalM HeysRF Inappropriate lactation. Br Med J 1969 4 236 5388733 PubMed