Mechlorethamine and Breastfeeding

Summary of use during lactation

Most sources consider that mothers receiving antineoplastic therapy should not breastfeed, especially with alkylating agents such as mechlorethamine.[1] Because of the potential for serious adverse reactions in the breastfed infant, breastfeeding from mechlorethamine mothers should not breastfed during therapy with mechlorethamine therapy, including topical application.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

References

1. PistilliB BellettiniG GiovannettiE Chemotherapy, targeted agents, antiemetics and growth-factors in human milk: How should we counsel cancer patients about breastfeeding? Cancer Treat Rev 2013 39 207 11 23199900 PubMed