Lactulose and Breastfeeding

Summary of use during lactation

No information is available on the clinical use of lactulose during breastfeeding. Lactulose is poorly absorbed orally, and it has been safely given directly to infants as a prebiotic and as a diagnostic agent.[1,2] If a mother requires lactulose, no special precautions are required.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

References

1. Koivusaari K, Niinistö S, Nevalainen J, et al. Infant feeding, gut permeability, and gut inflammation markers. J Pediatr Gastroenterol Nutr 2023;76:822–9.36913717 PubMed
2. Mingat SX, Ehara T, Nakamura H, et al. Comparative study of prebiotics for infants using a fecal culture system: Insights into responders and non-responders. Nutrients 2024;16:3347.39408314 PubMed