Glimepiride and Breastfeeding

Summary of use during lactation

Because no information is available on the use of glimepiride during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with glimepiride.[1,2]

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

Alternative drugs to consider

Acarbose, Glipizide, Glyburide, Insulin, Metformin, Miglitol

References

1. EverettJA Use of oral antidiabetic agents during breastfeeding. J Hum Lact 1997 13 319 21 9429368 PubMed
2. BerlinCM BriggsGG Drugs and chemicals in human milk. Semin Fetal Neonatal Med 2005 10 149 59 15701580 PubMed