Summary of use during lactation
No information is available on the use of givinostat during breastfeeding. Because it is 96% bound to human plasma proteins, amounts in milk are likely to be very low. If a mother requires givinostat, it is not a reason to discontinue breastfeeding. Until more data become available, givinostat should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Monitor the breastfed infant for diarrhea, vomiting, bruising, excessive bleeding from cuts, and blood in the stool.
Drug levels in milk and infant serum
Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.
Effects in breastfed infants
Relevant published information was not found as of the revision date.
Effects on lactation and breastmilk
Relevant published information was not found as of the revision date.
Source: Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, NCBI Bookshelf. Check LactMed for the most recent revision.
Medical disclaimer: This page is for qualified healthcare professionals and is a decision-support aid only. It does not replace clinical judgement, local protocols or product information. Verify every dose and threshold before use. See the full Medical Disclaimer.