Emapalumab and Breastfeeding

Summary of use during lactation

No information is available on the clinical use of emapalumab during breastfeeding. Because emapalumab is a large protein molecule with a molecular weight of about 147,000 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract.[1] Until more data become available, emapalumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

References

1. Anderson PO. Monoclonal antibodies during breastfeeding. Breastfeed Med 2021;16:591-333956488 PubMed