Echothiophate and Breastfeeding

Summary of use during lactation

No information is available on the use of echothiophate ophthalmic drops during breastfeeding. Because echothiophate is a quaternary ammonium compound, it is not likely to pass into the breastmilk or reach the bloodstream of the infant.[1]

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release, and have variable effects on serum prolactin.[2,3] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

References

1. JohnsonSM MartínezM FreedmanS Management of glaucoma in pregnancy and lactation. Surv Ophthalmol 2001 45 449 54 11274697 PubMed
2. ClarkeG FallCH LincolnDW Effects of cholinoceptor antagonists on the suckling-induced and experimentally evoked release of oxytocin. Br J Pharmacol 1978 63 519 27 566601
3. MüllerEE LocatelliV CellaS Prolactin-lowering and -releasing drugs: Mechanisms of action and therapeutic applications. Drugs 1983 25 399 432 6133737 PubMed