Dobutamine and Breastfeeding

Summary of use during lactation

No information is available on the use of dobutamine during breastfeeding. Because of its poor oral bioavailability and short half-life, any dobutamine in milk is unlikely to affect the infant.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information in nursing mothers was not found as of the revision date. Unlike dopamine, dobutamine infusion does not affect serum prolactin concentration in infants and in adult males.[1,2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

References

1. FilippiL PezzatiM PoggiC Dopamine versus dobutamine in very low birthweight infants: Endocrine effects. Arch Dis Child Fetal Neonatal Ed 2007 92 F367 71 17329276 PubMed
2. SchillingT GrundlingM StrangCM Effects of dopexamine, dobutamine or dopamine on prolactin and thyreotropin serum concentrations in high-risk surgical patients. Intensive Care Med 2004 30 1127 33 15138671 PubMed