Dihydroergotamine and Breastfeeding

Summary of use during lactation

No information is available on the clinical use of dihydroergotamine during breastfeeding. Because it might cause adverse effects in the infant and decrease the milk supply, most authorities consider ergotamine to be contraindicated during nursing.[1-3] The manufacturer of the dihydroergotamine nasal spray recommends that nursing mother should not breastfeed during treatment and for 3 days after the last dose. Any milk that is pumped during this time should be discarded.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

Alternative drugs to consider

Eletriptan, Rizatriptan, Sumatriptan, Zolmitriptan

References

1. DavanzoR BuaJ PaloniG Breastfeeding and migraine drugs. Eur J Clin Pharmacol 2014 70 1313 24 25217187 PubMed
2. MacGregorEA Migraine in pregnancy and lactation. Neurol Sci 2014 35 Suppl 1 61 4 24867839 PubMed
3. AndersonPO Migraine drug therapy during breastfeeding. Breastfeed Med 2019 14 445 7 31347910 PubMed