Danazol and Breastfeeding

Summary of use during lactation

No information is available on the use of danazol during breastfeeding, and it is considered to be contraindicated during breastfeeding.[1-3] An alternate drug is preferred.

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

Alternative drugs to consider

(Hereditary Angioedema) C1-esterase inhibitor

References

1. Busse PJ, Christiansen SC, Riedl MA, et al. US HAEA Medical Advisory Board 2020 guidelines for the management of hereditary angioedema. J Allergy Clin Immunol Pract 2021;9:132–50.e3.32898710 PubMed
2. Maurer M, Magerl M, Betschel S, et al. The international WAO/EAACI guideline for the management of hereditary angioedema-The 2021 revision and update. Allergy 2022;77:1961–90.35006617 PubMed
3. Grumach AS, Gadir N, Kessel A, et al. Current challenges and future opportunities in patient-focused management of hereditary angioedema: A narrative review. Clin Transl Allergy 2023;13:e12243.37227422 PubMed