Clotrimazole and Breastfeeding

Summary of use during lactation

Because has poor absorption from the skin and vagina and has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including after topical application to the nipples. It has been used orally in infants with thrush, sometimes successfully after nystatin has failed.[1] Any excess cream or ointment should be removed from the nipples before nursing. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug levels in milk and infant serum

Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.

Effects in breastfed infants

Relevant published information was not found as of the revision date.

Effects on lactation and breastmilk

Relevant published information was not found as of the revision date.

Alternative drugs to consider

Fluconazole, Miconazole, Nystatin

References

1. JohnstoneHA MarcinakJF Candidiasis in the breastfeeding mother and infant. J Obstet Gynecol Neonatal Nurs 1990 19 171 3 2319366 PubMed
2. NotiA GrobK BiedermannM Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol 2003 38 317 25 14623482 PubMed