Summary of use during lactation
No information is available on alpelisib during breastfeeding. Because the drug is 89% protein bound, amounts in milk are likely to be low. Because of possible infant toxicity, the manufacturer recommends that breastfeeding be discontinued during alpelisib therapy and for 1 week after the final dose.
Drug levels in milk and infant serum
Maternal Levels. Relevant published information was not found as of the revision date. Infant Levels. Relevant published information was not found as of the revision date.
Effects in breastfed infants
Relevant published information was not found as of the revision date.
Effects on lactation and breastmilk
Relevant published information was not found as of the revision date.
Source: Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, NCBI Bookshelf. Check LactMed for the most recent revision.
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